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Since circulating HTY in humans is mainly present as sulfate and glucuronide conjugates after oral intake, future studies should also clarify whether these metabolites contribute to the reported antidiabetic and anti-obesity effects (Fig

Low methionine levels can affect the production of A-adenosylmethionine (SAMe), a major methyl donor for the central nervous system and an essential nutrient required for the production of neurotransmitters

PPAR- antagonists, such as T0070907 and GW9662, have been demonstrated to interfere with cancer cell metabolism, apoptosis, and migration, enhancing the efficacy of anticancer drugs [399, 400]

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